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Diflucan

CLASS and MECHANISM of Action

Generic "Diflucan" kills the fungi that are causing an infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As Generic "Diflucan" causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.

Active Ingredients: Fluconazole
Inactive Ingredients: Microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium.

What is Generic "Diflucan" PRESCRIBED For?

Generic "Diflucan" is an antifungal medication. It is used to treat fungal infections. It is used to treat yeast infections of the mouth, throat, and esophagus; vaginal yeast infections; fungal Urinary Tract Infections; pneumonia caused by yeast; and fungal infections throughout the whole body and in the blood. Generic "Diflucan" is also used to prevent fungal infections from occurring in people with suppressed immune systems such as cancer chemotherapy patients, organ transplant patients, and AIDS patients. Generic "Diflucan" may also be used for purposes other than those listed in this medication guide.

How Should I Take Generic "Diflucan"?

How much medicine you take and how often you take it depends on many factors, including the condition being treated, your age, and weight. Take this medication exactly as prescribed, and continue taking it for as long as your doctor instructs. You may begin to feel better after the first few days; but it takes weeks or even months of treatment to completely cure certain fungal infections.

Diflucan tablets should be stored at normal room temperature. Avoid exposing them to temperatures above 86°F.

What are the CONTRAINDICATIONS for taking Generic "Diflucan"?

Do not take Generic "Diflucan" if you are pregnant or breast feeding! DO NOT TAKE Generic "Diflucan" IF YOU HAVE LIVER DISEASE.
Generic "Diflucan" is contraindicated in anyone with liver function abnormalities, liver disease, hepatitis or any other medical disorder of liver function including but not limited to cirrhosis of the liver, liver cancer, jaundice etc. should not take Generic "Diflucan".
Generic "Diflucan" is contraindicated in anyone with hypersensitivity to any other azole antifungal agent
Do not take Generic "Diflucan" for vaginal candida yeast infections if you are HIV positive, have a severely compromised immune system or are undergoing chemotherapy
Do not take Generic "Diflucan" if you are experiencing Fever, pain in the lower abdomen, back or either shoulder or if you have a foul-smelling vaginal discharge.

If you have any questions about your medical condition, consult your primary care physician before taking Generic "Diflucan".

What Happens if I MISS A DOSE?

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take double doses.

What happens if I OVERDOSE?

Symptoms of a Generic "Diflucan" overdose include confusion, hallucinations, paranoia, decreased movement, decreased breathing, tearing eyes, drooling, urinary incontinence, seizures, and death.

What are the possible SIDE EFFECTS of Generic "Diflucan"?

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect: Abdominal pain; Diarrhoea; Excess gas in the stomach and intestines (flatulence); Nausea and vomiting; Indigestion (dyspepsia); Headache; Rash; Alteration in taste, Liver disorders, Alteration in results of liver function tests, Dizziness; Seizures; Hair loss (alopecia); Decrease in the number of white blood cells or platelets in the blood; Raised levels of cholesterol in the blood; Decrease in the level of potassium in the blood (hypokalaemia); Severe skin reactions; Allergic reactions.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

What other drugs can INTERACT with Generic "Diflucan"?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
This medicine should not be taken in combination with any of the following medicines: cisapride, terfenadine.

The anti-blood-clotting effect of anticoagulants such as nicoumalone and warfarin may be enhanced by Generic "Diflucan". As this may increase the risk of bleeding, people taking an anticoagulant medicine should have their blood clotting time (INR) monitored if they also take Generic "Diflucan".
The antibiotic rifampicin (used for tuberculosis) lowers the blood level of Generic "Diflucan". Your doctor may need to prescribe you a larger than normal dose of Generic "Diflucan" if you need both these medicines.
Generic "Diflucan" may increase the blood levels of the following medicines: benzodiazepines, eg midazolam (this may cause increased drowsiness, and people taking both medicines may need a lower dose of benzodiazepine); ciclosporin (monitoring of ciclosporin blood levels is recommended); phenytoin (phenytoin blood levels should be monitored if you need both medicines; your doctor may need to reduce your phenytoin dose); repaglinide; rifabutin; sulphonylureas used for diabetes, eg glibenclamide, glipizide (this does not usually affect blood sugar control, but may rarely cause hypoglycaemia in some people); tacrolimus; theophylline; zidovudine (also known as AZT).

Additional Information

The effects of Generic "Diflucan" during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Generic "Diflucan" appears in breast milk and could affect a nursing infant. If Generic "Diflucan" is essential to your health, your doctor may advise you to stop breastfeeding until your treatment with Generic "Diflucan" is finished.
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