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Duphalac

CLASS and MECHANISM of Action

Generic "Duphalac" contains the active ingredient lactulose, which is a type of medicine called an osmotic laxative. Generic "Duphalac" is made up of sugar molecules which are broken down by the bacteria that live in the lower part of the gut. This leads to the contents of the gut becoming more acidic. The acidification of the contents of the gut causes a reduction in the absorption of a chemical called ammonia. The presence of ammonia in the gut causes water to be drawn into the lower bowel, which causes an increase in the water content and volume of the stools, therefore relieving constipation.

Active Ingredients: Lactulose
Inactive Ingredients: Galactose, epilactose, fructose, galactose, hydrogen peroxide, sodium hidroxide and small amounts of lactose.

What is Generic "Duphalac" PRESCRIBED For?

Generic "Duphalac" is a complex sugar-like laxative derived from lactose. It helps to treat chronic constipation and to treat or prevent hepatic encephalopathy or coma (brain disorders that result from liver disease).

How Should I Take Generic "Duphalac"?

Take Generic "Duphalac" syrup by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one; household spoons are not always accurate. You can mix Generic "Duphalac" with fruit juice or water before taking. Do not take your medicine more often than directed.
    Constipation:
  • Adults (including the elderly): initially 15 ml twice daily
  • Children 5 to 10 years: 10 ml twice daily
  • Children under 5 years:5 ml twice daily
  • Babies under 1 year: 2.5 ml twice daily
All dosages should subsequently be adjusted to the needs of the individual. Each dose may if necessary be taken with water or fruit juices, etc.
    Hepatic encephalopathy:
  • Adults (including the elderly): Initially 30 - 50 ml (6-10 x 5 ml spoonfuls) three times a day. Subsequently adjust the dose to produce two or three soft stools each day.
  • Children: no dosage recommendations for this indication.
Elderly patients over 65 years old need smaller doses to reduce possible side effects.

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away if solution becomes dark or cloudy, which may be caused by high storage temperature. Too low storage temperature may make the product difficult to pour.

What are the CONTRAINDICATIONS for taking Generic "Duphalac"?

Contraindicated in patients with galactosaemia and in cases of gastro-intestinal obstruction.
    Before taking this medication, tell your doctor if you:
  • are diabetic,
  • require a diet low in galactose, or
  • require a proctoscopy or colonoscopy.
You may not be able to take Generic "Duphalac" , or you may require a lower dose or special monitoring if you have any of the conditions listed above.

What Happens if I MISS A DOSE?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What happens if I OVERDOSE?

Symptoms of a Generic "Duphalac" overdose are not known, but diarrhea, abdominal cramps, and possible complications of dehydration from excessive diarrhea would be expected.

What are the possible SIDE EFFECTS of Generic "Duphalac"?

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
  • Diarrhoea
  • Abdominal cramps
  • Excess gas in the stomach and intestines (flatulence)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

What other drugs can INTERACT with Generic "Duphalac"?

    The following drugs may interact with Generic "Duphalac":
  • antacids
  • other laxatives
  • neomycin
Tell your prescriber or health care professional: about all other medicines you are taking including nonprescription medicines; if you are a frequent user of drinks with caffeine or alcohol; if you smoke; or if you use illegal drugs. These can affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

Additional Information

Generic "Duphalac" may not produce any result for between 24 and 48 hours. Do not take Generic "Duphalac" for more than one week unless your prescriber or health care professional has prescribed a regular schedule for you.
Drink plenty of water with each dose of Generic "Duphalac".
If you are taking other medication, take Generic "Duphalac" at least 2 hours before or afterwards so that it will not interfere with your other medicines.
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