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Generic "Duphaston" is a type of synthetic hormone, which is similar to one of the body's main sex hormones (progesterone). Progesterone is the body hormone that plays an important part in the developing of the healthy endometrium (endometrium is absolutely essential in the occurrence of a pregnancy). This hormone produces a couple of times during a normal menstrual period. It also helps in the maintaining of the womb lining, (making it easier to avoid the risk of spontaneous abortion or of miscarriage) in the case of women who have had many miscarriages.

Active Ingredients: Dydrogesterone
Inactive Ingredients: Lactose, maize starch, hypromellose, magnesium stearate, colloidal anhydrous silica, macrogol 400 and titanium dioxide (E171)

Generic "Duphaston" is normally prescribed in the treatment of several medical conditions like the ones listed below:
• Miscarriage
• Bleeding or abdominal pain during pregnancy
• Abdominal pain (usually associated with dysmenorrhoea or with menstrual periods)
• Endometriosis
• No menstrual periods
• Irregular periods
• Female infertility
• PMS

Generic "Duphaston" can also be prescribed by doctors in the treatment of other medical conditions that have not been mentioned here.

Swallow the tablet(s) with water, with or without food. The number of tablets you take and the days you take them on will depend on what you are being treated for.

The usual doses are:
• To relieve pre-menstrual syndrome (PMS): The usual starting dose is one tablet twice a day for 15 days from days 12 to 26 of your monthly cycle.
• To stop heavy or prolonged periods: Take one tablet twice a day for five to seven days. Your doctor may prescribe you estrogen treatment as well, because this type of bleeding usually happens just before the menopause when your body is making less estrogen.
• To prevent heavy or prolonged periods: Take one tablet twice a day from days 11 to 25 of your monthly cycle. Your doctor may prescribe estrogen as well (as explained under the last heading).
• To ease period pains: Take one tablet twice a day from days 5 to 25 of your monthly cycle.
• To ease period pains in young girls: The usual dose is one tablet twice a day, but follow your doctor's instructions. Your doctor will tell you when to stop taking the treatment.
• To relieve symptoms of endometriosis (womb tissue that grows outside of the womb): Take one tablet two or three times a day, either from days 5 to 25 of your cycle, or every single day.
• To overcome amenorrhoea (the absence of periods): Take one tablet twice a day from days 11 to 25 of your monthly cycle. Your doctor will also prescribe estrogen from days 1 to 25 of your monthly cycle.
• For infertility or irregular periods: Take one tablet twice a day from days 11 to 25 of your monthly cycle. You should take the tablets until you have had at least 6 periods. If you become pregnant, tell your doctor.
• For threatened miscarriage: Take four tablets at once, then one tablet every 8 hours until your symptoms stop. If they do not stop, or they return during treatment, increase the dose to 2 tablets every 8 hours and keep taking them for a week.
• If you have had miscarriages before: Start taking the tablets as early as possible, preferably before you become pregnant. Take one tablet twice a day from days 11 to 25 of your monthly cycle until you become pregnant, and continue taking them (one twice a day) until you have been pregnant for 20 weeks. After that, your doctor may ask you to take the tablets less often.

Do not store above 30°C.

Do not take Generic "Duphaston" if any of the following applies:
• you have, or have had, or your doctor thinks you might have, breast cancer
• you have had or your doctor thinks that you might have a tumour which is made worse by progestogens (e.g. meningioma)
• you have, or you are being treated for, a blood clot in an artery or in a vein in your leg or anywhere else (a deep vein thrombosis), or a blood clot that has travelled to your lung or other parts of your body (an embolus), or you have had one of these conditions in the past
• you have angina, or you have had a heart attack or stroke
• you have or have had serious liver disease
• you have or have recently had abnormal liver test results
• your doctor told you that you have porphyria (an inherited metabolic disorder)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

Generic "Duphaston" should be taken in or on a regular basis. If you are following a treatment with Generic "Duphaston" , try not to miss any of your doses. If you happen to miss one take it as soon as possible and continue with your regular schedule. You should not take in a double dose of this drug unless you are instructed by your physician to do so.

The symptoms of an overdosage with Generic "Duphaston" have not been clearly established. If you suspect that you are suffering from an overdose with this drug you should contact your local poison control center, inform your personal physician.

Generic "Duphaston" can also induce other side effects (more common and less serious) such as:
• Nausea
• Headache
• Bloating
• Breast tenderness
• Dizziness
• Skin reactions (itch and rash)
• Menstrual spotting (blood) between two periods

These mild side effects shouldn't stop you from continuing with your treatment. However, you should inform your doctor at once.
Other side effects may also occur when you take Generic "Duphaston". Inform your physician immediately if you experience anything unusual while taking this drug.

If you have to follow a treatment with another drug, even is they are simple vitamins, herbal products or minerals, please ask for your doctor's consent before doing so. He might want to monitorize the way that your body responds to the treatment or might want to make dosage adjustments to the normal dose of Generic "Duphaston". that he or she would prescribe to a patient with your condition.

Pregnancy: There is no known risk in pregnancy. Generic "Duphaston" is indicated for threatened or habitual abortion, until the twentieth week of pregnancy.
Lactation: Small amounts are expected to be excreted, but exact amounts are unknown. There have been no reports of adverse experiences.