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Florinef

CLASS and MECHANISM of Action

Generic "Florinef" promotes increased reabsorption (rapid and complete) of sodium and loss of potassium from renal distal tubules. Generic "Florinef" is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity.

Active Ingredients: Fludrocortisone acetate
Inactive Ingredients: Calcium phosphate, corn starch, lactose, magnesium stearate, sodium benzoate, and talc.

What is Generic "Florinef" PRESCRIBED For?

Sometimes the body experiences conditions in which they cannot or does not produce a sufficient amount of steroids, like Addison's disease, and salt-losing adrenogenital syndrome. Generic "Florinef" functions in the body by treating the said conditions. Generic "Florinef" could also be used in other purposes not mentioned here.

How Should I Take Generic "Florinef"?

Infants and Children: 0.05-0.1 mg/day
Adults: 0.1-0.2 mg/day with ranges of 0.1 mg 3 times/week to 0.2 mg/day
Addison's disease: Initial: 0.1 mg/day; if transient hypertension develops, reduce the dose to 0.05 mg/day.
Salt-losing adrenogenital syndrome: 0.1-0.2 mg/day
Take once-a-day dose with food in the morning. Limit intake of caffeine or stimulants.
Store at room temperature; avoid excessive heat.

What are the CONTRAINDICATIONS for taking Generic "Florinef"?

Generic "Florinef" lessens the body's ability to fight infection so avoid taking this medication if you have serious bacterial, viral, or fungal infection.
Talk to your doctor first before taking this medication if you have kidney disease, diabetes mellitus, myasthenia gravis, ulcerative colitis, hypothyroidism, high blood pressure or heart disease, liver disease, tuberculosis, psychiatric conditions, stomach ulcers, osteoporosis, or any other medical conditions.
If you have diabetes, monitor serum glucose closely and notify prescriber of changes; this medication can alter glycemic response.
Your doctor might not allow you to take Generic "Florinef", adjust your dose or require you a specials monitoring during the treatment. It is unknown whether this medication could cause harm to an unborn baby.
Talk to your doctor first before taking Generic "Florinef" if you are pregnant.
Talk to your doctor first before taking this medication if you are breast-feeding an infant because this passes in breast milk.

What Happens if I MISS A DOSE?

In case you miss a dose of this medication, take the missed dose as soon as you recall but if it is almost time for the next dose, skip the missed dose and take the next dose that was regularly scheduled. Avoid taking a double dose of this medication.

What happens if I OVERDOSE?

Some of the signs of overdose with Generic "Florinef" are weight gain, swelling or water retention, high blood pressure and low levels of potassium in the blood. Taking a large dose of this medication, even once is unlikely to cause symptoms or death.

What are the possible SIDE EFFECTS of Generic "Florinef"?

Some of the serious side effects of Generic "Florinef" are allergic reactions such as closing of your throat, difficulty in breathing, swelling of the lips and hives; severe or continuing headache; sudden weight gain; dizziness or fainting; swelling of the feet or ankles; increased blood pressure; and difficulty in breathing.
If you experience any of the said serious side effects, stop taking Generic "Florinef". Some other side effects of this medication are muscle weakness or joint pain, glaucoma, cataracts, thinning of your skin, nausea or stomach upset, fatigue, increased hunger or thirst, problems with diabetes control, osteoporosis, round face, and changes in behavior. If you experience any of the said side effects, inform your doctor about it.
Report weakness, change in menstrual pattern, vision changes, signs of hyperglycemia, signs of infection, other persistent side effects, or worsening of condition.

What other drugs can INTERACT with Generic "Florinef"?

  • antiinflammatory drugs
  • barbiturate medicines for inducing sleep or treating seizures
  • bosentan
  • certain heart medicines
  • male hormones
  • phenytoin
  • rifampin water pills.
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works.

Additional Information

Take exactly as directed. Do not take more than prescribed dose and do not discontinue abruptly; consult prescriber. Take with or after meals.
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