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Motrin

CLASS and MECHANISM of Action

Generic "Motrin" tablets, a nonsteroidal anti-inflammatory drug is available in 400 mg and 600 mg tablets for oral administration. Generic "Motrin" is used for the management of mild to moderate pain, fever, and inflammation. Pain, fever, and inflammation are promoted by the release in the body of chemicals called prostaglandins. Ibuprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower levels of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

Active Ingredients: Ibuprofen
Inactive Ingredients: colloidal silicon dioxide, carnauba wax, croscarmellose sodium, hypromellose, lactose, microcrystalline cellulose, magnesium stearate, propylene glycol, titanium dioxide.

What is Generic "Motrin" PRESCRIBED For?

Generic "Motrin" has three actions: it reduces fever, relieves pain and fights inflammation.
    Typical uses are:
  • teething,
  • earaches,
  • sunburn,
  • fevers,
  • headaches and
  • sore muscles.

How Should I Take Generic "Motrin"?

When taking any medication, always read and follow the package instructions carefully. For adults taking Generic "Motrin": Take 1 caplet or tablet every 4 to 6 hours while symptoms persist. If pain or fever does not respond to 1 caplet or tablet, 2 caplets or tablets may be used, but do not exceed 6 caplets or tablets in 24 hours, unless directed by a doctor. The smallest effective dose should be used. Take with food or milk, if occasional and mild heartburn, upset stomach or stomach pain occurs with use. Consult a doctor if these symptoms are more than mild or if they persist.

Store between 20-25 degrees C / 68-77 degrees F.

What are the CONTRAINDICATIONS for taking Generic "Motrin"?

  • Do not use
    - if you have ever had an allergic reaction to any other pain reliever / fever reducer
    - right before or after heart surgery
  • Ask a doctor before use if you have
    - problems or serious side effects from any pain reliever / fever reducer
    - stomach problems that lasts or come back, such as heartburn, upset stomach, or stomach pain
    - ulcers
    - bleeding problems
    - high blood pressure
    - heart or kidney disease
    - taken a diuretic
    - reached age 60 or older
  • Ask a doctor or pharmacist before use if you are
    - taking any other drug containing an NSAID - prescription or nonprescription
    - taking a blood thinning - anticoagulant - or steroid drug
    - under a doctor's care for any serious condition
    - taking any other drug
  • When using this product
    - take with food or milk if stomach upset occurs
    - long term continuous use may increase the risk of heart attack or stroke
  • Stop use and ask a doctor if
    - you feel faint, vomit blood, or have bloody or black stools
    - These are signs of stomach bleeding.
    - pain gets worse or lasts more than 10 days
    - fever gets worse or lasts more than 3 days
    - stomach pain or upset gets worse or lasts
    - redness or swelling is present in the painful area
    - any new symptoms appear

What Happens if I MISS A DOSE?

Important is to remember not to exceed 6 tablets in 24 hours, unless is directed by a doctor.

What happens if I OVERDOSE?

If an overdose is suspected the local emergency should be contacted immediately.

What are the possible SIDE EFFECTS of Generic "Motrin"?

The most frequent type of adverse reaction occurring with Generic "Motrin" tablets is gastrointestinal.
    Generic "Motrin" can cause serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. The most common side effects from ibuprofen are:
  • rash,
  • ringing in the ears,
  • headaches,
  • dizziness,
  • drowsiness,
  • abdominal pain,
  • nausea,
  • diarrhea,
  • constipation and
  • heartburn.
NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Ibuprofen may cause ulceration of the stomach or intestine, and the ulcers may bleed.

What other drugs can INTERACT with Generic "Motrin"?

Generic "Motrin" is associated with several suspected or probable interactions that can affect the action of other drugs. Generic "Motrin"may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Generic "Motrin" may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When Generic "Motrin" is used in combination with aminoglycosides [for example, gentamicin (Garamycin)] the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced.

Additional Information

Do not exceed 6 tablets in 24 hours, unless directed by a doctor.
Do not take longer than 10 days, unless directed by a doctor.
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