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Generic "Phenegran" is a phenothiazine in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine). However, unlike the other drugs in this class, Generic "Phenegran" is not used clinically as an anti-psychotic.
It works by decreasing the effects of histamine, a chemical the body releases in response to certain irritants. Histamine narrows air passages in the lungs and contributes to inflammation. Antihistamines reduce itching and swelling and dry up secretions from the nose, eyes, and throat.

Active Ingredients: Promethazine HCl.
Inactive Ingredients: Lactose, magnesium stearate, and methylcellulose, saccharin sodium.

Generic "Phenegran" is used to prevent motion sickness, nausea or vomiting, itching associated with allergies or for sedation.

Generic "Phenegran" tablets are taken by mouth. They can be taken with or without food. For prevention of motion sickness, a tablet should be used 30 to 60 minutes before the motion begins and then every 8 to 12 hours as needed. For sedation, it is given at bedtime. For other problems, for example, itching, it can be given every 4 to 8 hours.

Generic "Phenegran" tablets should be stored between 2° (36°F) and 30°C (86°F).

Generic "Phenegran" tablets should not be used in children less than two years of age because it can depress respiration and has caused fatalities in children under two. It should be used cautiously in children older than two.
Generic "Phenegran" is contraindicated in patients that are allergic to promethazine or any of the ingredients in this medication. Patients with lung symptoms including asthma should avoid taking Generic "Phenegran".

If you are taking Generic "Phenegran" on a regular schedule, take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not double dose.

If Generic "Phenegran" overdose is suspected seek medical attention immediately.

Here are some side effects that may happen when take Generic "Phenegran": blurred vision, dizziness, drowsiness, dry mouth, increased or decreased blood pressure, nausea, rash, sedation, vomiting.
Talk to your doctor if something bothers you.

Generic "Phenegran" should not be used along with: MAO (mono-amine oxidase) inhibitor-class of antidepressants; Antihistamines; Phenothiazines; Tricyclic antidepressants.
Excessive sedation may occur when Generic "Phenegran" is combined with other medications that depress the central nervous system (brain). Such drugs include ethanol, barbiturates, anti-anxiety medications, sedatives, other phenothiazines, and narcotic pain medications.

When Generic "Phenegran" is used with antipsychotics, metoclopramide (Reglan), and amoxapine (Asendin) an increase in the risk of certain neurologic reactions that affect movement of muscles, called extrapyramidal symptoms (EPS) may happen.

Generic "Phenegran" is not recommended for use during breast-feeding because they can stimulate newborns or cause seizures in premature infants.

Keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.