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Generic Serevent is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. It is currently available as a metered-dose inhaler (MDI) or a proprietary "disk-styled" inhaler that releases a powdered form of the drug. Generic Serevent is an agonist at beta-2 receptors. These receptors are present in large numbers in the lungs and are located on bronchiolar smooth muscle. Stimulation of beta-2 receptors in the lung causes relaxation of bronchial smooth muscle, which produces bronchodilation and a resultant increase in bronchial airflow. Generic Serevent can inhibit the bronchoconstriction produced by histamine, methacholine, and exercise. In addition, Generic Serevent appears to inhibit the late phase of allergen-induced bronchoconstriction, which usually appears after the bronchodilating effects of the shorter-acting agents have resolved. The extended action of Generic Serevent is due to its long, lipophilic side chain. This side chain appears to bind to an exosite present only near beta-2 receptors. Binding to this exosite allows the active portion of the molecule to remain at the receptor site and continually engage and disengage with the receptor, therefore providing a long duration of action.

Active Ingredients: Serevent (salmeterol xinafoate) Inhalation Aerosol contains salmeterol xinafoate. The active component of the formulation is salmeterol base

Generic Serevent is a prescription medication used to prevent airway spasms (called bronchospasms) caused by asthma. The medicine is also used to treat these spasms in people who have chronic obstructive pulmonary disease (COPD Generic Serevent comes in two forms, the Generic Serevent Diskus and the Generic Serevent inhaler. The Diskus is approved for treating both asthma and COPD, while the inhaler is approved only for treating asthma.

Generic Serevent Inhalation Aerosol should be administered by the orally inhaled route only. It is recommended to "test spray" Generic Serevent Inhalation Aerosol into the air 4 times before using for the first time and in cases where the aerosol has not been used for a prolonged period of time (i.e., more than 4 weeks). SEREVENT DISKUS does not replace fast-acting inhalers for sudden symptoms and should not be taken more than twice a day. Store the Generic Serevent at room temperature away from direct sunlight and freezing temperatures.

Do not use Generic Serevent to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use another, faster-acting inhalation medication to treat an asthma attack.
Generic Serevent is has been shown to increase the risk of asthma-related death. It is critical that you use only the prescribed dose of this medicine and follow all patient instructions for safe use of the medication. Talk with your doctor about your individual risks and benefits in using Generic Serevent.
Do not use a second form of Generic Serevent or use a similar inhaled bronchodilator such as formoterol (Foradil) unless your doctor has told you to.

Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.

If you use this medication to treat COPD, do not use the medicine for longer than 6 months unless your doctor has told you to.

Do not stop using Generic Serevent without first talking to your doctor. Your asthma symtoms may get worse after you stop using the medication.

Use the medication as soon as you remember, then wait 12 hours before using the medication again. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Generic Serevent overdose include muscle cramps, dry mouth, sleep problems (insomnia), tremors, chest pain, fast or irregular heartbeats, feeling light-headed, fainting, or seizure (convulsions).

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects: chest pain, fast or pounding heartbeats, tremors, shaking, or restless feeling; wheezing, choking, or other breathing problems after using this medication; skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or worsening asthma symptoms.

Other, less serious side effects may be more likely to occur, such as: headache, dizziness, lightheadedness, or insomnia; sweating; nausea, vomiting, or diarrhea; or dry mouth or throat irritation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Generic Serevent can increase blood pressure, heart rate, and cause chest pain and excitement, especially if used in higher doses than recommended or used in those with coronary heart disease or high blood pressure. Generic Serevent should not be combined with Tricyclic antidepressants because of additive effect on the vascular system. In rare instances, Generic Serevent can induce paradoxical worsening of bronchospasm (which can be life-threatening). If this occurs, Generic Serevent should be discontinued, and the doctor notified immediately. Rare allergic reactions to Generic Serevent can cause skin rash, hives, swelling, bronchospasm, and anaphylaxis.

Use With Spacer or Other Devices: The safety and effectiveness of Generic Serevent Inhalation Aerosol when used with a spacer or other devices have not been adequately studied.
Never breathe into the DISKUS.
Never take the DISKUS apart.
Always ready and use the DISKUS in a level, flat position.
Do not use the DISKUS with a spacer device.
Never wash the mouthpiece or any part of the DISKUS. Keep it dry.
Always keep the DISKUS in a dry place.