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Sporanox

CLASS and MECHANISM of Action

Generic Sporanox is a drug used in the treatment of fungal infections, such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis). The mechanism of action of Generic Sporanox is the same as the other azole antifungals: it inhibits the fungal cytochrome P450 oxidase-mediated synthesis of ergosterol.

Active Ingredients: itraconazole
Inactive Ingredients: gelatin, hydroxypropyl methylcellulose, polyethylene glycol 20,000, starch, sucrose, titanium dioxide, FD&C Blue No. 1, FD&C Blue No. 2, D&C Red No. 22 and D&C Red No. 28.

What is Generic "Sporanox" PRESCRIBED For?

The treatment of fungal infections which are isolated to a small area of the body (localized) or throughout the body (systemic). It is active against fungal infections such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis). Generic Sporanox capsules are used to treat three types of serious fungal infection: blastomycosis, histoplasmosis, and aspergillosis. Blastomycosis can affect the lungs, bones, and skin. Histoplasmosis can affect the lungs, heart, and blood. Aspergillosis can affect the lungs, kidneys, and other organs. The drug is also prescribed for onychomycosis, which infects the toenails and fingernails. Additionally, Generic Sporanox is used against fungal infections in people with weak immune systems, such as AIDS patients.

How Should I Take Generic "Sporanox"?

Use Generic Sporanox Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions. Take Generic Sporanox Capsules after a full meal. Take Generic Sporanox Capsules for 1 week, and then do not take Generic Sporanox Capsules for 3 weeks, and then repeat the same cycle, unless directed otherwise by your doctor. This pack contains enough medicine for 1 week Do not take antacids within 1 hour before or 2 hours after taking Generic Sporanox Capsules. Take Generic Sporanox Capsules at least 2 hours before proton pump inhibitors (eg, omeprazole). To clear up your infection completely, continue taking Generic Sporanox Capsules for the full course of treatment even if you feel better in a few days. Do not miss any doses. Generic Sporanox Capsules works best if it is taken at the same time each day.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed

What are the CONTRAINDICATIONS for taking Generic "Sporanox"?

    Do NOT use Generic Sporanox Capsules if:
  • you are allergic to any ingredient in Generic Sporanox Capsules
  • you are being treated for a certain type of fungal infection (onychomycosis) and you also have a history of heart problems (eg, congestive heart failure) or are pregnant or may become pregnant
  • you are taking aldosterone blockers (eg, eplerenone), cisapride, dofetilide, ergot alkaloids (eg, ergotamine), erythromycin, H1 antagonists (eg, astemizole, terfenadine), HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), levacetylmethadol (levomethadyl), midazolam, nevirapine, pimozide, quinazolines (eg, alfuzosin), quinidine, rifabutin, rifampin, triazolam, or 5-HT receptor agonists (eg, eletriptan)
Contact your doctor or health care provider right away if any of these apply to you.

What Happens if I MISS A DOSE?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What happens if I OVERDOSE?

Seek emergency medical attention if you think you have used too much of Generic Sporanox.
Symptoms may include changes in behavior; hallucinations; seizures; slowed breathing.

What are the possible SIDE EFFECTS of Generic "Sporanox"?

Generic Sporanox can cause congestive heart failure (condition in which the heart cannot pump enough blood through the body) . Tell your doctor if you have or have ever had heart failure; a heart attack; an irregular heartbeat; any other type of heart disease; lung, liver, or kidney disease; or any other serious health problem. If you experience any of the following symptoms, stop taking Generic Sporanox and , call your doctor immediately: shortness of breath, coughing up white or pink phlegm, weakness, excessive tiredness , fast heartbeat, swelling of the feet, ankles, or legs; and sudden weight gain.

What other drugs can INTERACT with Generic "Sporanox"?

    If Sporanox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sporanox with any of the following:
  • Acid-blocking drugs such as cimetidine
  • Alprazolam
  • Atorvastatin
  • Blood-thinning drugs such as warfarin
  • Clarithromycin
  • Cyclosporine
  • Diazepam
  • Disopyramide
  • Dofetilide
  • Digoxin
  • Eletriptan
  • Erythromycin
  • Indinavir
  • Buspirone
  • Busulfan
  • Caffeine-containing agents such as migraine drugs
  • Calcium channel blockers such as nifedipine
  • Carbamazepine
  • Cilostazol
  • Docetaxel
  • Isoniazid
  • Levacetylmethadol
  • Lovastatin
  • Methylprednisolone
  • Midazolam
  • Nevirapine
      Oral diabetes medications such as glyburide and glipizide
    • Phenobarbital
    • Phenytoin
    • Pimozide
    • Saquinavir
    • Simvastatin
    • Sirolimus
    • Tacrolimus
    • Triazolam
    • Quinidine
    • Rifabutin
    • Rifampin
    • Ritonavir
    • Trimetrexate
    • Vinblastine

    Additional Information

    Generic Sporanox Capsules may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Generic Sporanox Capsules. Using Generic Sporanox Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
    LAB TESTS, including liver function tests, may be required to monitor therapy. Be sure to keep all doctor and lab appointments.
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