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Generic Sustiva is a non-nucleoside reverse transcriptase inhibitor and is used as part of highly active antiretroviral therapy for the treatment of a human immunodeficiency virus (HIV) type 1.Like other drugs for HIV, Sustiva works by impairing the virus's ability to multiply. However, when taken alone it may prompt the virus to become resistant. Generic Sustiva is therefore always taken with at least one other HIV medication, such as Retrovir or Crixivan. Even when used properly, it may remain effective for only a limited time. Generic Sustiva may also be used for purposes other than those listed in this medication guide.

Active Ingredients: efavirenz
Inactive Ingredients: lactose monohydrate, magnesium stearate, sodium lauryl sulfate, and sodium starch glycolate.

Generic Sustiva in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection. This indication is based on two clinical trials of at least one year duration that demonstrated prolonged suppression of HIV RNA.

Generic Sustiva is taken by mouth as a capsule. The normal adult dose is 600 milligrams (mg) once a day at bedtime. Generic Sustiva is available in capsules of 50 mg, 100 mg, and 200 mg. Most adults will take 3 of the 200 mg capsules at a time. It is recommended that you take Generic Sustiva on an empty stomach, at bedtime. This dosing should result in the fewest side effects. High-fat foods increase Generic Sustiva levels and should be avoided before taking a dose. Store at room temperature, away from sunlight and moisture. Do not store in the bathroom.

Do not take generic Sustiva with the following medications:
Ergot-based migraine medications such as D.H.E. 45, Ergostat, and Sansert
Midazolam (Versed)
Triazolam (Halcion)
The combination could cause serious even life-threateningeffects such as heart irregularities or disrupted breathing. If Sustiva gives you an allergic reaction, you cannot continue using it.

Take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not double the dose.

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Generic Sustiva overdose may include confusion, lack of balance or coordination, severe mood or behavior changes, or thoughts of suicide.

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Sustiva.
Side effects may include:
Abnormal dreaming, abnormal thinking, amnesia, agitation, confusion, cough, diarrhea, dizziness, drowsiness, fatigue, feelings of well-being, fever, hallucinations, headache, impaired concentration, insomnia, loss of identity, nausea, skin rash, vomiting.

Be sure to avoid combining Generic Sustiva with Versed, Halcion, or any of the migraine medications listed under "Why should this drug not be prescribed?"

If Generic Sustiva is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Generic Sustiva with the following:
• Alcohol
• Amprenavir (Agenerase)
• Atazanavir
• Carbamazepine (Tegretol)
• Clarithromycin (Biaxin)
• Indinavir (Crixivan)
• Itraconazole (Sporanox)
• Ketoconazole (Nizoral)
• Methadone (Dolophine)
• Nelfinavir (Viracept)
• Oral Contraceptives containing ethinyl estradiol, such as Estinyl, Ovcon, and Ovral
• Phenobarbital
• Phenytoin (Dilantin)
• Rifabutin (Mycobutin)
• Rifampin (Rifadin and Rimactane)
• Ritonavir (Norvir)
• Saquinavir (Fortovase and Invirase)
• St. John's Wort
• Voriconazole (antifungal)
• Warfarin (Coumadin).

Though Generic Sustiva can slow the progress of HIV, it is not a cure. HIV-related infections remain a danger, so frequent checkups and tests are still advisable