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Generic Theo-24 has two distinct actions in the airways of patients with reversible obstruction: smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects). While the mechanisms of action of Generic Theo-24 are not known with certainty, studies in animals suggest that bronchodilation is mediated by the inhibition of two isozymes of phosphodiesterase (PDE III and, to a lesser extent, PDE IV) while non-bronchodilator prophylactic actions are probably mediated through one or more different molecular mechanisms that do not involve inhibition of PDE III or antagonism of adenosine receptors. Some of the adverse effects associated with Generic Theo-24 appear to be mediated by inhibition of PDE III (e.g., hypotension, tachycardia, headache, and emesis) and adenosine receptor antagonism (e.g., alterations in cerebral blood flow). Generic Theo-24 increases the force of contraction of diaphragmatic muscles. This action appears to be due to enhancement of calcium uptake through an adenosine-mediated channel.

Active Ingredients: theophylline
Inactive Ingredients: edible ink (which contains synthetic black iron oxide, FD&C Blue No. 1, FD&C Blue No. 2, FD&C Yellow No. 6, D&C Yellow No. 10, FD&C Red No. 40), ethylcellulose, gelatin, pharmaceutical glaze, colloidal silicon dioxide, starch, sucrose, talc, titanium dioxide, and coloring agents: 100 mg-includes FD&C Yellow No. 6; 200 mg-FD&C Red No. 3 and D&C Yellow No. 10; 300 mg-FD&C Blue No. 1 and FD&C Red No. 40; 400 mg-FD&C Red No. 40 and D&C Red No. 28.

Generic Theo-24 is indicated for the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, e.g., emphysema and chronic bronchitis.

Take Theo-Dur exactly as prescribed. Do not change the dose, the time you take it, or how often you take it without consulting your doctor. Generic Theo-24 must be taken either 1 hour before or 2 hours after a meal. You may take the capsule whole or open it and empty the contents onto a spoonful of food that is soft but not hot. Without chewing, immediately swallow the spoonful of food and follow it with a glass of cool water or juice. Always take the complete contents of the capsule. When taking Theo-Dur, you should avoid large amounts of caffeine-containing beverages, such as tea or coffee.
Store at room temperature. Keep the container tightly closed. Protect from excessive heat, light, and moisture. Make sure this medicine is kept out of reach of children.

Do not take Generic Theo-24 if you have ever had an allergic reaction to it or similar drugs.
Do not take Generic Theo-24 if you have an active peptic ulcer or a seizure disorder such as epilepsy.

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

If overdose of Generic Theo-24 is suspected seek emergency medical attention.
Symptoms of a Theo-24 overdose include nausea, vomiting, headache, insomnia, tremor (shaking hands or twitching), restlessness, seizures, and irregular heartbeats.

If you experience any of the following serious side effects, stop taking Generic Theo-24 and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); seizures; increased or irregular heartbeats; or severe nausea or vomiting.

Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take Generic Theo-24 and talk to your doctor if you experience: slight nausea, decreased appetite, or weight loss; restlessness, tremor, or insomnia; or headache, lightheadedness, or dizziness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Before taking Generic Theo-24, tell your doctor if you are using any of the following drugs: carbamazepine (Carbatrol, Tegretol); cimetidine (Tagamet); enoxacin (Penetrx); ephedrine or similar medications found in cold medicine or diet pills; erythromycin (E.E.S., E-Mycin, Ery-Tab); fluvoxamine (Luvox); propranolol (Inderal, InnoPran); rifampin (Rifadin, Rifater, Rifamate, Rimactane); St. John's wort; or thiabendazole (Mintezol).

There are many other medicines that can interact with Generic Theo-24. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Do not share Generic Theo-24 with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep Generic Theo-24 out of the reach of children and pets. If using this medicine for an extended period of time, obtain necessary refills before your supply runs out.