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Generic Zanaflex is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain.

Active Ingredients: tizanidine hydrochloride
Inactive Ingredients: silicon dioxide colloidal, stearic acid, microcrystalline cellulose and anhydrous lactose.

It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label as a sleep aid, seizure inhibitor, and for some symptoms of fibromyalgia

Take this medication by mouth as directed. When you start this medication, your dosage will probably need to be increased slowly by your doctor to reduce side effects, especially dizziness and/or drowsiness. Ask your doctor or pharmacist how to use this medication correctly, and follow all instructions carefully. This medication usually starts to work in 1 to 2 hours and wears off after 6 to 8 hours. Generic Zanaflex can be taken every 6 to 8 hours, but you should not take more than 36 milligrams a day or more than 3 doses in 24 hours. The dosage is based on your medical condition and response to therapy.
Store away from light and moisture at room temperature at 77 degrees F (25 degrees C). Do not store in the bathroom. Keep this and all medications away from children and pets.

Do not use this medication if you are allergic to Generic Zanaflex, or if you are also taking the antidepressant fluvoxamine (Luvox) or the antibiotic ciprofloxacin (Cipro).
Before using Generic Zanaflex, tell your doctor if you are allergic to any drugs, or if you have: liver disease; kidney disease; high or low blood pressure; or a history of "Long QT syndrome.

If you have any of these conditions, you may not be able to use Generic Zanaflex, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Generic Zanaflex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. In older adults, Generic Zanaflex may take much longer to clear from the body. Follow your doctors instructions about your specific dosage and medication schedule.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting, or coma.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:
• feeling light-headed, fainting, slow heart rate;
• hallucinations, confusion, unusual thoughts or behavior;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
• burning or pain when you urinate.

Less serious side effects may be more likely to occur, such as:
• drowsiness or dizziness;
• feeling anxious or nervous;
• numbness or tingling;
• stomach pain, diarrhea, constipation, vomiting;
• fever;
• dry mouth;
• muscle weakness, back pain;
• increased muscle tone or spasms; or
• sweating or skin rash.

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effects.

Before taking Generic Zanaflex, tell your doctor if you are using any of the following drugs:
• acyclovir (Zovirax);
• cimetidine (Tagamet);
• famotidine (Pepcid);
• ticlopidine (Ticlid),
• zileuton (Zyflo);
• birth control pills;
• antibiotics such as enoxacin (Penetrex), gatifloxacin (Tequin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), ofloxacin (Floxin), sparfloxacin (Zagam), trovafloxacin (Trovan), or norfloxacin (Noroxin);
• blood pressure medications such as clonidine (Catapres), guanabenz (Wytensin), guanfacine (Tenex), or methyldopa (Aldomet); or
• heart rhythm medications such as amiodarone (Cordarone, Pacerone), mexiletine (Mexitil), propafenone (Rhythmol), and verapamil (Calan, Covera, Isoptin).

This list is not complete and there may be other drugs that can interact with Generic Zanaflex. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children and pets. If using this medicine for an extended period of time, obtain necessary refills before your supply runs out.