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Generic Centchroman
Generic "Centchroman" is a SERM, or selective estrogen receptor modulator.
Ormeloxifene
CLASS and MECHANISM of Action Generic "Centchroman" is a SERM, or selective estrogen receptor modulator. In some parts of the body, its action is estrogenic, in other parts of the body, its action is anti-estrogenic (e.g., uterus, breasts. It causes an asynchrony in the menstrual cycle between ovulation and the development of the uterine lining, although its exact mode of action is not well defined. In clinical trials, it caused ovulation to occur later than it normally would in some women, but did not affect ovulation in the majority of women, while causing the lining of the uterus to build more slowly. It speeds the transport of any fertilized egg through the fallopian tubes more quickly than is normal. Presumably, this combination of effects creates an environment such that if fertilization occurs, implantation will not be possible.
Active Ingredients: Ormeloxifene What is Generic "Centchroman" PRESCRIBED For? Generic "Centchroman" may be used as a contraceptive or as a treatment for dysfunctional uterine bleeding.
Generic "Centchroman" has also been found effective as an anti-breast cancer agent. Multicentric trials in stage III/IV breast cancer patients, who were not responsive to other modalities of therapy, were found to respond to Generic "Centchroman" with an overall responsive rate of about 56%. | |||||||||||||||||||||||||
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