Cheap Sildenafil Citrate

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Generic Sildenafil Citrate

Sildenafil citrate is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension.

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CLASS and MECHANISM of Action

Sildenafil citrate is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension.. Part of the physiological process of erection involves the parasympathetic nervous system causing the release of nitric oxide (NO) in the corpus cavernosum of the penis. NO binds to the receptors of the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation (vasodilation) in the corpus cavernosum, resulting in increased inflow of blood and an erection.
Sildenafil citrate is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. The molecular structure of sildenafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Without sexual stimulation, and therefore lack of activation of the NO/cGMP system, Sildenafil citrate should not cause an erection. Sildenafil citrate is metabolised by hepatic enzymes and excreted by both the liver and kidneys.

Active Ingredients: Sildenafil Citrate
Inactive Ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #2 aluminum lake

What is Sildenafil citrate PRESCRIBED For?

Sildenafil citrate is prescribed to treat erectile dysfunction (impotence) in men. It can help many men who have ED get and keep an erection when they become sexually excited (stimulated).
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