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Generic Zestril
Generic Zestril is an angiotensin-converting enzyme (ACE) inhibitor which blocks the production of a hormone (chemical signal carried in the blood) called angiotensin II.
CLASS and MECHANISM of Action Generic Zestril is an angiotensin-converting enzyme (ACE) inhibitor which blocks the production of a hormone (chemical signal carried in the blood) called angiotensin II. Lisinopril competes with angiotensin I for its binding site on the angiotensin-converting enzyme (ACE), an enzyme which converts angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative feedback mediator for renin activity, lower angiotensin II plasma levels result in decreased blood pressure and increased plasma renin activity. Baroreceptor reflex mechanisms, stimulated by the fall in blood pressure, release kininase II, an enzyme identical to ACE that degrades bradykinin, a vasodilator.
Active Ingredients: lisinopril Inactive Ingredients: calcium phosphate, magnesium stearate, mannitol, red ferric oxide, starch. What is Generic "Zestril" PRESCRIBED For? Generic Zestril is used to treat high blood pressure (hypertension), heart failure and complications of diabetes.
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